Telomeres are caps at the end of our DNA that protect chromosomes.At six and 12 months of age, the infants were brought to the lab to engage in mildly stressful tasks.This may be one mechanism that connects psychological stress to telomere length and ultimately physical health.In our view, these results show how important it is to fund effective maternal mental health treatment and early childhood policies. We also collected information on how many depression symptoms mothers were feeling.Telomeres and healthHow does stress affect our cells? One area of burgeoning research focuses on telomeres.This can elicit stress in infants, as they rely on their caregivers to not only feed them, but to also soothe their emotions.For our study we recruited 48 mothers with 12-week-old infants and followed these families until the infants were 18 months old.Cells that are exposed to cortisol have shorter telomeres and less telomerase, which is the enzyme responsible for maintaining the ends of telomeres.Our study We examined whether increasing maternal depressive symptoms affected infant stress and later cell health.During each visit, we measured infants stress by collecting saliva samples to look at changes in cortisol..
Since the length of telomeres is affected by our genetics and age, theyre sometimes thought of as part of a biological clock that reflects the age of our cells.An estimated one in nine women experience symptoms of postpartum depression.Worsening depression symptoms in mothers related to greater infant cortisol stress responses between 6 and 12 months of age.In addition, infants with higher cortisol stress responses were more likely to have shorter telomeres at 18 months of age, indicating greater cellular wear and tear.Fostering positive experiences between infants and their mothers – as well as providing affordable, scientifically supported treatment services for mothers experiencing depression – may allow infants to move toward a healthier life trajectory.Early relationships between mothers and their infants can influence health across the lifespan, for better or worse.Indeed, adolescents with depressed mothers have heightened cortisol stress responses and shorter telomeres than their peers, even when the adolescents themselves are not depressed. The same can be said of your telomeres.This early stress may put young children on track for the early onset of poor health outcomes. However, scientists do not completely understand how these environments get under the skin to shape health.This article was originally published by The Conversation .Our latest paper, published in November, shows a possible link between increasing depression symptoms in mothers and cellular damage in their infants.Theyre analogous to the plastic tips at the end of shoelaces that keep laces from unraveling.For example, in the still face experiment, mothers alternated between playing with their infant and not reacting to their infants bids for attention.One way to study how early stress may influence health is to look at how infants respond to their parents stress.When we experience stress, our bodies release a hormone called cortisol, which influences our emotional responses as well as our energy metabolism, learning and memory.
As telomeres shorten over time, people are more likely to experience a host of negative health outcomes, such as cardiovascular disease, dementia, diabetes, cancer, obesity and even death. For example, adults who report more household dysfunction and abuse during their childhood are more likely to suffer disease as adults. Studies suggest that infants exposed to maternal depression may be less likely to engage socially and experience more negative emotion.These symptoms – including mood swings, fatigue and reduced interest in activities – can make it difficult for mothers to bond with their diy deer fence newborns.Better mental health While these findings are preliminary and should be replicated with a larger group of infants, our results highlight how patterns of health across the lifespan may be influenced in the first 18 months of life.In essence, these plastic caps keep laces functional.Infancy is a sensitive period, when individuals are strongly influenced by their environment.This process may explain how psychological stress is converted to biological wear and tear.Interestingly, telomeres can degrade more quickly when a person suffers from psychological stress.Those with healthy and supportive relationships during early life are better at handling stress and regulating their emotions.The silver lining is that infancy is a sensitive developmental period, when humans are especially responsive to their environments.